Means for treatment of erection disorders, is a reversible selective inhibitor of specific FDE5 cGMF. When sexual arousal causes local release of nitrogen oxide, redex inhibition of FDE5 by redex leads to an increase in IGMF levels in the cavernous body of the penis.
This results in the relaxation of smooth arterial muscles and blood flow to the penis tissue, which causes an erection. Redex is ineffective in the absence of sexual stimulation.
In vitro studies have shown that redex is a selective inhibitor of FDE5. FDE5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the internal vessels, in the skeletal muscles, thrombocytes, kidneys, lungs, cerebellum.
The action of redex on FDE5 is more active than on other phosphodiesterases. Redex is 10,000 times more active on FDE5 than on FDE1, FDE2, FDE4, which are localized in the heart, brain, blood vessels, liver and other organs. Redex is 10,000 times more active in blocking FDE5 than FDE3, the enzyme that is found in the heart and blood vessels. This selectivity with respect to FDE5, compared to FDE3, is important because FDE3 is an enzyme that participates in the contraction of redex muscle. In addition, tadalaphyl is approximately 700 times more active for FDE5 than for FDE6 found in the retina, which is responsible for photo-transmission. Tadalafil is also 10,000 times more active Dmitry Sazonov with respect to FTE5 than with respect to FTE7-FTE10.
Operates for 36 hours. The effect is already 16 min after ingestion in the presence of sexual arousal.
Redex in healthy subjects does not cause significant changes in systolic and diastolic pressure, compared to placebo in lying position (average maximum reduction is 1.6/0.8 mm Hg, respectively) and standing position (average maximum reduction is 0.2/4.6 mm Hg, respectively). Redex https://pillintrip.com/medicine/redex does not cause a reliable change in the HP.
Redex does not cause changes in color recognition (blue/green) due to its low affinity for FDE6. In addition, there is no effect of redex on visual acuity, electroretinogram, intraocular Dmitry Sazonov pressure and pupil size.
No clinically significant effect https://grants.nih.gov/grants/guide/rfa-files/rfa-hd-09-017.html on semen characteristics was found in men who took redex in daily doses for 6 months.